Pharmacological MRI in Mice with the Rapid Steady State T1-Technique and Intraperitoneal Contrast Agent Administration

Keywords

access according acquisition addition adiabatic administered administration advantages agent agents already anatomical animal approaches approved barrier berger blood brain carbonic catheters cerebral challenges chart classification coil committee compartment confined confinement confirms connected continuously contrast coronal coupling density difficulty drugs duration dynamic enabling equals equilibrium equipped ethic excitation experiment extension feasible finding flow fraction gain grading head healthy hemisphere hypothetical increasing induced inhibitor injected injection injections institute institutional intact intravenous inversion lasting least limitations located mapping maps material matrix mechanism mice minutes models mouse muscle neurological noise noninvasive normalized outlined pharmacological pharmacologically pose post preloaded prepared previously prior protocol proton providing pulse quantification quantitative radiology rapid rats recently reception recovery regional reliably repeated repetition require respectively route safely sample scanner selective sensitive sensitivity sensory significance since slices space start starts statistical steady stimuli surface thalamus tissue tissues transmission traumatic tumor typical useful vascular volume window