Intra-Scan Reproducibility of White Matter Perfusion in Dementia Using Pseudo-Continuous Arterial Spin Labeling

Keywords

academic achieved acquisition advanced aging although analyses analyze anatomical arterial assesses available background bland blood brain capture cerebral channel clinical clinically cognitive cohort coil columns conducted confidence continuous currently defined degradation degrees delay dementia disease disorders disregarding divided dotted duration dutch dynamics encourages excluded extra flow focus focuses fraction furthermore generally gradient gray head heterogeneous hypothesize impairment include index indicate interval intra investigators involved labeling larger limited long many marker mask masks matrix measured medical mild minutes model negative neurobiology neurological neurology noise north occur onset paired pairwise parker partial patient patients perfusion physiological plots post potential preceding previously processing proven pseudo pulse pulses quantification radiology rather registered relatively relevant reliable reliably repeatability repeated reported reproducibility resolution respectively robustness saturation scaled scanner scanning sense short shot slices software solid spin studies subject substantially subtracted suggest suppression thresholds timescales trust types variation varies vary volume weeks white whole windows wise women years