Sampling Duration in DCE-MRI: in vivo Comparison Using Data Acquired Within a Clinical Phase I Study

Keywords

acquisition additional agreement although always analyses analytic application appropriate assessing automatically breathing built cancer carried clinical cohort compartment computer concentration conditions consists constant contrast core coronal correlation covering curve curves custom decrease decreased defined dependency dependent describes developed development driven duration durations dynamic enhanced enough equal equals examinations example expression extended fact findings fitting free function functional in vivo independent inhomogeneous initial inversion investigated larger length lesion lesions like limited liver long mainly martin matrix medical metastasis minimize minutes model mostly movement novel observations oriented package part patient patients percentage permeability phys physiological possibly previously processing product protocol published quantification quantitative reach real received recovery required residual respectively response rise routine sampled sampling semi separate sets several significance simulation simulations since slice smaller software spanning statistical steps studies subgroup subset support surface target tendency therapeutics took tool tracked transfer treatment typical uniform valuable verification view whole