Meeting Banner
Abstract #3495

Improved Temporal Resolution and Reduced Geometric Distortions Using Interleaved 3D Spiral Acquisition for Arterial Spin Labeling Imaging

Youngkyoo Jung1, 2, Megan Johnston2

1Radiology, Wake Forest School of Medicine, Winston-Salem,, NC, United States; 2Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC, United States

3D ASL imaging provides high SNR benefit over 2D methods. Segmented 3D acquisition methods covering the entire k-space during multiple labeling periods are often preferred to reduce blurring in the slice encoding direction. However, applications of the segmented acquisition are limited to baseline perfusion imaging. We propose an interleaved 3D spiral FLASH imaging method that collects the entire k-space within a single labeling period which offers high temporal resolution, and reduces geometric distortions. We also investigated the trade-off between the number of interleaves and SNR benefit. The proposed method would be beneficial to various ASL applications.

Keywords

acceptable acquisition advantage advantages allows application applications applied applying arterial background bars became benefit biomedical blood blurring cerebral close collect collected collects containing contamination contaminations control covering deep degrees delay delays desired developed deviations distortions duration effectively emphasizing encoded encoding engineering entire error example excitation excitations experiment flash flow forest frontal geometric gradient gradients gray healthy improve improved include indicate initial interleave interleaved interleaves interpreted inversion keeping labeling lobes long maps matrix measured medicine minimize needed normalized offers parallel partial particularly perfusion period periods physiological played popular post potential preferable preferred preparation produce propose proposed pulses quickly radiology rapid reconstruction recovery reduce reduced reduces representative require requires resolution resolutions scheme schemes school segment segmented sensitive sensitivity severe short shorter shot simplicity since skipped slice space spatial speed spin spiral stack steps subject subjects sufficient suitable suppress tagged tagging take temporal theoretical tissue trade trajectories typically useful variable volume wake whereas yields