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Abstract #3225

Quantitative 7T Phase Imaging in Presymptomatic Huntingtons Disease

A. C. Apple1, J. M. Lupo1, A. Jakary1, K. Wong2, D. A. C. Kelley3, G. Kang2, M. Geschwind2, S. J. Nelson1, Christopher Hess4

1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States; 2Department of Neurology, University of California, San Francisco, San Francisco, CA, United States; 3GE Healthcare, Global Applied Sciences Labroratory; 4Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States

This work analyzed the local field shift representing iron content in Huntington's disease (HD) patients and controls. This work suggests that local field shift may be a useful biomarker for early stage HD and an indication of the role of iron in the pathogeneisis of HD.

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Keywords

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