Using 1H MR Spectroscopy to Evaluate the Neurochemical Effect of Transgenic TauP301L Suppression by Doxycycline in RTg4510 Mouse

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achieved addition adjusted adult aged aggregation amount analyzed anesthetized animals assess automatically behavioral blunted brain brains care carol cells chow chronic chronically coil completion concentration conception consistent contamination continuous continuously decreased degree delays dependent designed despite detected developing development developmental diminishes distinguish divided duration early eddy either embedded environment evaluate existed express expression female field find findings finishing fitted formation fully helpful hicks horizontal human illustrated impairment indicate induce induces inducible induction investigate journal laboratory localized longitudinal loss made magnet measures memory metabolites mice mild minimal mixed model moderate month months mouse mouth natal neuron neuronal paraffin pathological pathology phenotype positioned post postnatal power prevent previous processes protein protocols pyramidal qualified reduction regional report reported repress reverse scout significantly since spectral spectrum staining strain studies subgroups suggesting suppress suppressed suppression surface switched table tangle term tool treated treatment type units untreated variable volume volumetric water weeks width wild yang yield younger