Preliminary Evidence of DKI Abnormalities in the Hippocampus of a Mouse Model of Down Syndrome

Keywords

abnormalities acknowledgments acquisition additional aging ahead anisotropy approximately arise assess avoid axial barriers bars behavior believed better beyond brain brains called cell characterized chromosome cognitive cognitively common complexity considered control correlation cycle dead decrease deficits dementia depending depression derived described despite developing development diffusion diffusional diffusivity directional disabilities diseases drug enlarged enlargement estimator except exhibit extends extracellular fact fractional frank genome gradient humans illustrates impaired impairment important in vivo indicators info innervations institute interpretation intracellular kurtosis learning life little long loss manually maps maria masked matrix measures mechanisms medical membranes memory metrics mice minutes model models months morphological morphologically morphology mouse natl neurons neuropathology parametric part patterns physics preliminary presence print programmed progressive psychiatry quantifying radial rearrangement receive reduced related reported reports respiration review sensitive shot since slice slices software south space spines statistical stress stroke structural structures studied studies supported syndrome system table targets term thereby tissue tissues want water white zero