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Abstract #3013

Detection of Colorectal Liver Metastases : Sensitivity of T2-Weighted and Diffusion-Weighted Imaging Using Histopathological Examination as Method of Reference in a Rat Model.

Mathilde Wagner1, 2, Lon Maggiori, 23, Maxime Ronot1, 2, Valrie Vilgrain1, 2, Yves Panis, 23, Bernard Edgar Van Beers1, 2

1Radiology, Beaujon hospital, Clichy, France; 2INSERM U773, Clichy, France; 3Colorectal surgery, Beaujon hospital, Clichy, France

The purpose of the study was to compare the sensitivity of T2-weighted and diffusion-weighted imaging (DWI) in detecting colorectal liver metastases in a rat model with precise histopathological correlations. DWI detection rate was higher than T2-weighted imaging detection rate (p = 0.001). After stratification according to metastasis average diameter, DWI detection rate was higher than T2-weighted imaging detection rate for metastases with a diameter between 0.3 and 1.2 mm, but not for metastases smaller than 0.3 mm or larger than 1.2 mm. This study shows the better sensitivity of DWI relative to T2-weighted imaging for detecting liver metastases.

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