Hemodynamics Under Pharmacological Challenge in Rat Brain: Comparison of BOLD, CBV and CBF Using Bicuculline

Keywords

acquisition actions activation activity acute additionally advantages agent agents allows almost alternating anesthetized animal appears approaches approved artery artificially assessed balloon better binding bold brain calculating care challenge challenges characteristics characterize circuitry collect collected collectively committee complementary console consortium contrast correlate cortex curve decay density described design despite detected deviation directly disadvantages discovery distinct distribution drug duration dynamics endpoint exert experimental extract fair feasibility flow funded furthermore generated henry hypothesized importantly increasingly indirectly induced infusion injected institutional interestingly interfaced intubated inversion known larger long male manner maps matrix medicine minutes model modest much neural neuronal noise normalized optimization optimized oxygen patterns perfusion pharmaceuticals pharmacological physiology project prolonged prominent quantitative rats receptor recovery regional response responses returned revealed revision robust rodent sensitive sharp short shot since slice slices slower stabilized star stimulus studies suggesting suppress system tail technical thalamus translational transmissions triggering underlying underpin undershoot understanding useful vary vein ventilated whereas width