Evaluation of a New QBOLD Approach to Map Local Blood Oxygen Saturation in Non Human Primates

Keywords

acquisition activity addition anatomy anesthesia anesthetized animals appear appears applied approaches berger biomedical blood body bold bolus brain carried challenges channel characterized christen coils combination combines comparable considered conversely correct correspond decay deeper dependent depth depths detect deviation diseases dynamic echoes electrical emission enough evaluate evaluated evaluation eventually exam expected facility field final fitting fraction fully function gadolinium gamma gaseous good gradient gray head hemoglobin human humans inhomogeneities injection institute intramuscular iron literature local macroscopic male mapped maps mask masks match materials measured model monitor next noise normalization normalized note oxide oxygen oxygenated oxygenation passage perfusion positron preliminary primate primates proposed protocol quantitative rats realigned realized receive received recently reduced reflect reported representative reproducible resolution respectively saturation scanner segmentation sensitive separate significance significantly slices spatial spatially spin stable steady strength stroke student studies susceptibilities tissue tomography transmit validate validated variate volume weighing white whole yielded