Meeting Banner
Abstract #2822

Identification of State Changes from Spontaneous Fluctuations in FMRI Data

Meghan Robinson1, Javier Gonzalez-Castillo1, Souheil Inati2, Daniel Handwerker1, Peter Bandettini1, 2

1Section on Functional Imaging Methods, NIMH, NIH, Bethesda, MD, United States; 2functional MRI Facility, NIMH, NIH, Bethesda, MD, United States

The brain is continuously adapting to respond to the environment. In the course of a rest scan, subjects are expected to engage in different cognitive states for variable periods of time (i.e., relaxing, planning dinner, napping, etc.). Each of these states brings the brain into a different pattern of overall connectivity. Still, some level of stability is expected for the periods when subjects remain in a given cognitive state. Here, we propose a way to automatically identify such cognitive states looking at how the fMRI signal from different cortical regions pass in-and-out of synchrony with each other as time progresses.

Abstract PDF E-Poster Video

Keywords

according accurately adapting analytical assumption attention automatically belong belongs best better blocks blue boxes brain broken capturing changing characteristics classified clustering cognitive coherent color combine components computed configuration configurations connectivity considered consisted constructed contiguous continuously correction correlated correlation correlations corresponds cortex cortical course deciding default define description detection dinner distance distant dynamic endeavors engage environment euclidean expected fall feature flickering fluctuations focusing frequency functional functionally generated good head healthy help hierarchical hour identified identify include individual intersect investigating localizer long look matrix minute mode moments motion nature network networks next organization pair part pass patterns periods positioned positioning potential power processed processes processing progresses regional relaxing rely remain representative resolution respond resting scale scanner scanning scores section series serve slice smoothing spatial spectra spectral spontaneous stability stable stationarity steps still structural subject subjects subsequently subset suggests synchrony tapping task tasks temporal terms tools transitions trying uniquely variable visual ward whole wise