Meeting Banner
Abstract #2067

Optimization of Diffusion-Weighted FMRI at 3T MRI Compare with BOLD-FMRI

Li-Ming Hsu1, Kuan-Hung Cho2, Cyril Poupon3, Denis Le Bihan3, Ching-Po Lin, 14

1Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; 2Instrumentation Resource Center, National Yang-Ming University, Taipei, Taiwan; 3NeuroSpin, IFR 49 CEA Saclay, Gif-sur-Yvette, France; 4Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan

To optimize the diffusion-fMRI at different b-values by considering the signal performance compared with BOLD-fMRI during visual stimulation. The results show that the DfMRI at b-value = 1,200 s/mm2 should be a better choice than b-value = 600 and 1,800 s/mm2. DfMRI could provides the chance to approach the neuron activation than hemodynamic response.

Keywords

accuracy achieved acquisition activated activating activation addition adopted anatomic better biomedical black blood bold carried cellular chance channel characteristics checkerboard choice clinical closer cluster coil comparing component considering consisted containing contiguous contrast corrected cortex cortical course courses crossing decay decreases defined design detecting diffusion discussed eight equals evaluating every experimental faster fields filter finer fissures five flickering flow frame functional furthermore gradient greater handicaps head healthy hence hung implies individual initial initially institute instrumentation investigate known largest listed localization long males maps material mechanisms might ming motion multiplied national neuron neuronal noise normalized offset optimization optimize overlap participated performance power primary probes psychological radiological reducing registered represent resolution resource respectively response resting rise root scanning sciences selected sensitivity session several significantly slice smaller smoothing software spatial spin square statistics stimulation stimuli stimulus studies subject sufficient suggest system table temporal tissue trial trials upper variation vascular visual volume water white whole yang