Meeting Banner
Abstract #2025

The Measurement and Interpretation of Intravoxel Incoherent Motion (IVIM) of Skeletal Muscle in vivo: Preliminary Results

Yoshikazu Okamoto1, Tomonori Isobe, Yuji Hirano2

1University of Tsukuba Hospital , Tsukuba, Ibaraki, Japan; 2University of Tsukuba hospital, Japan

The soleus muscle (SOL) and the flexor digitorum profundus muscle (FDP) was scanned to cover b-factors from 0 to 3,500 s/mm2 of diffusion weighted image. A statistical comparison between monoexponential and biexponential fits was performed, and a statistically improved fit (P < 0.05; F test) was observed in all cases. The fast and slow diffusion fractions and fast and slow apparent diffusion coefficient (ADCfast and ADCslow) were 0.92 } 0.05, 0.08 } 0.05, 1.68 } 0.14, and 0.26 } 0.17, for SOL, and 0.95 } 0.01, 0.05 } 0.01, 1.75 } 0.22, and 0.01 } 0.02, respectively, for FDP.

Keywords

addition additionally amount analyses anatomy apparent appear appears approaches approximately assessed assessing assessment axis best biopsy blood brain calf cell cells channel circular coefficients coil component components considered considering consist contamination coordinate cover decay decrease described diameter differ diffusion disappear either equation examine example excluded exercise experienced exponential exponentially extracellular extremely fast fits fitting flex focused fractions frequent functions generally greater healthy hospital house hypothesized improved in vivo incoherent indicate individual intensity interpretation intracellular invest japan largely long made massive materials matrix membrane micrometer microscopic might millimeter minutes mono moreover motion much muscle muscles occasionally occurs organs paired perfusion period personal plot preliminary primarily principle prostate published radiologist radiology recent recruited reflects release reported reproducibility respectively scale scanned semi setting settings shape shapes significance significantly skeletal slice slices slightly slow software space speed statistical statistically studies substance suggest surrounding table tensor transferred typical unique utility variation versus volunteer volunteers water whether year years