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Abstract #1997

Accelerated Kinetic ASL Using 3D Spiral TSE and Compressed Sensing

Li Zhao1, Xiao Chen1, Samuel W. Fielden1, Frederick H. Epstein1, John P. Mugler III2, Josef Pfeuffer3, Manal Nicolas-Jilwan2, Max Wintermark2, Craig H. Meyer1, 2

1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States; 2Radiology, University of Virginia, Charlottesville, VA, United States; 3Siemens, Erlangen, Germany

To achieve high SNR, we develop 3DTSE with stack spiral acquisition. To shorten scan time, compress sensing is modified to perform on spiral trajectory. CBF and MTT are estimated from dynamic data properly and off-line reconstruction with acceleration rate of 3 shows little difference.

Keywords

accelerated acceleration accuracy acquisition acute alternating artifacts assumption assumptions available averaging axes banding biomedical blood brain challenging chopping classic coefficient collected combined common compartment compressed constant constrained control corrected coverage crushers curve decay delay density develop domain done dynamic efficiently eliminate encoding engineering estimation excitation expected exploit exploiting fair fast flow foundation frame frames full fully funded future gives goal gradients improve include interleaves john kinetic label leading leaf limited made maps medical minutes model modeling parallel particular partition perfusion processed promise pulse pulses radiology rapid readout readouts reconstruction recovery reduction refocusing repetitively required resolution sampled sampling scanner selected sensing sensitizing setting short significantly slab slice slices solution space sparsity spatial spiral spirals stack strategy stroke sufficient suppress symmetrically tagging temporal train transform transit triggering trio underlying uniform useful white yield