Meeting Banner
Abstract #1848

Impact of Kurtosis Diffusion Weighted Imaging on the Detection of Liver and Kidney Abnormalities at 1.5 and 3 Tesla

Jan Hansmann1, Andreas Lemke2, Jens Wambsganss1, Mathias Meyer1, Miriam Reichert1, Stefan O. Schoenberg1, Ulrike I. Attenberger1

1Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Mannheim, BW, Germany; 2Computer Assisted Clinical Medicine, University Medical Center Mannheim, Mannheim, BW, Germany

Diffusion kurtosis parameter maps of the abdomen were obtained in 118 consecutive patients at 1.5 and 3 Tesla with 6 b-values (b=0-100-500-1000-1500-2000 s/mm). Kurtosis values in normal parenchyma and a variety of kidney and liver lesions (cysts, benign and malignant tumors) were assessed and compared using the Wilcoxon-Rang-Sum test. Results show statistically signifcant differences in kurtosis values between normal parenchyma and the assessed lesions. Thus, kurtosis imaging of liver and kidney lesions is feasible at 1.5 and 3 Tesla and allows for a differentiation of various lesions compared to normal parenchmya based on kurtosis values.

Abstract PDF

Keywords

abdominal abnormalities additional allows already alterations altered anatomical anisotropy artery assess assessed assisted background behavior benign bilateral black built cell central characterization clinical coded color complex computer conditions consecutive continue contrast cysts daily defined degree detection diagnostic differentiation diffusion diffusional dimensionless disease display enabling evaluation feasibility feasible fractional general haste hindered house identical impact important institute interactions inverted invest kidney kurtosis lesions liver living malignancy malignant maps masses materials measure medical medicine membranes molecules nervous nuclear often patients play post processes prospectively protocol proven quantification radiology rang reflecting reflection renal repetition respectively restriction role routine sided software statistically structural structures system tensor tissue trio tumor tumors underwent utility various vibe water