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Abstract #1730

Localized Filtering for Optimal Fat Suppression in Parallel 1H MRSI

MAGNA25Thomas Kirchner1, Anke Henning1, Peter Boesiger1

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland

A striking manifestation of the voxel-bleeding effect in MRSI in vivo is subcranial fat signal falsely appearing in a voxel in the center of the brain. We developed a localized filtering technique for the suppression of fat artefacts. Unlike k-space apodization techniques, we achieve artifact suppression without incurring fat signal spread at the edge of the object.

Keywords

accelerated achieved acquisition among analytical anatomical appealing appearing applied appropriate artifact artifacts assembled assigned best biomedical bleeding bound brain carries caused chemical choice coil compromises contaminations contributions control cost covariance direct displacement division edge effective efficient employed enabled enables encoding encountered equivalent exhibit exponential extracted falsely field filter filtered filtering filters fold former frequency function functions global hamming healthy henning identical illustrated imperfections indicated individual introducing investigation knowledge latter leads lobe local localized locally loss lost manifestation matrix medical mere metabolite minimized minimizing mixed noise novel nuclei object optimal overlapping pathologies peak peter press previous prior proton pulses quality rapid reaching real reconstructed reconstruction rectangular reduced removing residual response restricted retained sampling scaling selective selectively sense sensitivity shape shim simulating slice somewhat space spatial spatially spectra spectral spectrally spectrum spin spread still strong studies subtraction suppress suppression system target term theory together tumors unfolding uniformly version view wanted water window yield