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Abstract #1600

Cardiac Catheter Ablation Under Real Time MR Guidance: Initial Clinical Application

Peter Nordbeck1, 2, Meinrad Beer3, Marcus Wamuth1, Daniel Gensler2, Theresa Reiter1, Herbert Kstler3, Thomas Pabst3, Peter M. Jakob2, Mark E. Ladd4, Harald H. Quick5, Wolfgang R. Bauer1, Oliver Ritter1

1Internal Medicine I - Cardiology, University Hospital Wuerzburg, Wuerzburg, Germany; 2Experimental Physics V, University of Wuerzburg, Wuerzburg, Germany; 3Radiology, University Hospital Wuerzburg, Wuerzburg, Germany; 4Diagnostic and Interventional Radiology, University Duisburg-Essen, Essen, Germany; 5Medical Physics, University Erlangen-Nuernberg, Erlangen, Germany

Interventional electrophysiology (EP) for diagnosis and treatment of cardiac arrhythmia is currently performed under fluoroscopic guidance, which offers poor tissue contrast and limited feedback on therapy efficacy or complications. MR guided EP has the potential to solve many of these problems, but is technically challenging and accompanied by specific additional patient risks due to the technical equipment needed in the scanner room. Our group developed an EP setup for diagnosis and therapy of arrhythmia under real time MR guidance. The results from the first clinical applications in two patients with arrhythmia resistant to conventional therapy are presented.

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Keywords

ablation absence adapted addition address adjusted advanced adverse animal application applications arrhythmia arrhythmias assessment atrial beer benefit beyond capable cardiac cardiology cardiovascular catheter catheters causes circulation clinical combination components conditional console contrast crucial currently custom customized decades decisive delineation delivery described designed despite developed development diagnosis diagnostic directly early enhanced environment episodes equipment essential experimental fabricated feasibility filters flutter foundation functionality future guidance guided heart hiller hospital immediate improvements in vivo inability individually initial interactive interference internal intervention interventions irrigated isthmus leading lesion lesions little many mapping mark medical model monitoring monitors morbidity myocardium novel occurred often oliver operator opportunity pacing particularly passive patient patients peter physics platform potential prior procedural quick radiation radiology real recent refractory replaced reported revolutionized room safety sensing setup shortcomings simultaneous soft specially steerable studies successful sufficient support surface surmount surrounding systems technical therapeutic therapy though tissue tracking treatment typical utilization utilized validation visualization visualize vitro weaknesses whole