In-Vivo Temporal Characterization of Focal Openings of the Blood-Brain Barrier Using MR Guided Focused Ultrasound

Keywords

accuracy acoustic administration agents amounts anesthesia anesthetized animal animals another appeared approved around arrow barrier bars blood bone borders brain break breathed burst care cause characterization coil committee composed computer contrast control controlled currently damage decrease deep defined deliveries delivery depositing desired determine diffuse dislodge done duration elsewhere energy enhanced error every example experimental extended focal focused frequency grant guided heating hemisphere highest highly immediately important in vivo increasing induced initial injecting injection injections inside institutional intravenous invasive investigated kept larger least localized location longer loop mechanically medical metastases millimeter minimal minutes mixture modality model moved note open opened opening openings optimal organs percentage periods post precise preliminary pressure probe produce promising protocol quantification radiology rats regional represent resolution restricts since slice slight society solutions specifically spontaneously steady still studies sufficient suitable supported surface surrounding system temporal temporally therapeutic thrombus tissue transducer treatment trio tumor ultrasound underwent uterine venous vessels wait wider window