Meeting Banner
Abstract #1444

Simultaneous Detection of Blood Flow, MT Asymmetry, and MT Ratio in Human Skeletal Muscle

Sung-Hong Park1, Kyongtae Ty Bae1

1Radiology, University of Pittsburgh, Pittsburgh, PA, United States

In this article we evaluated the feasibility of alternate ascending/descending directional navigation (ALADDIN), a new imaging technique that provides interslice perfusion-weighted and MT asymmetry images, on human skeletal muscle. Subtraction artifacts in ALADDIN MT asymmetry images were suppressed by averaging signals over the readout gradient polarities. ALADDIN PW and MT asymmetry signals measured in muscle were about 10% and 30%, respectively, of those in brain, while MT ratio of muscle was similar to that of brain. Further studies are necessary to investigate clinical usefulness of simultaneous acquisition of blood flow, MT asymmetry, and MT ratio with ALADDIN in skeletal muscle.

Keywords

acquisition acquisitions agreement allows almost alternate although anterior appears appropriate arterial ascending assessment assist asymmetry averaging axial axis blood body bottom brain challenges characteristics clinical coil conditions consistent contrast contribution contributions covering datasets decreased delay descending detection directional distance duration dynamic dystrophy eddy effective either evaluate evaluated eventually experimental favorable feasibility feet flow frank free frequencies gradient gradients head healthy heterogeneous hong human improvement independent insignificant intrinsic investigate knowledge labeling linear literatures location long macromolecular magnetization material matrix measure medical metabolism middle modulations moving much muscle muscular navigation necessary negative offset park patients percent perfusion phantom physiology polarity positive posterior potential potentially previously radiology readout reception reconstructed regional relatively repeated repetitions reported represents researchers residual resolution respectively rows scanner scheme select sensitivity short significantly simultaneous simultaneously skeletal slice slow solutions spin studied studies subject subtraction summation sung suppressed suppression symmetric transfer transmission unit usefulness vascular versa vice volunteers weak white whole