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Abstract #1356

Fast Synchronous 3He/1H Dynamic Lung Imaging

Salma Ajraoui1, Jim M. Wild1

1University of Sheffield, Sheffield, Yorkshire, United Kingdom

In this work, dynamic 3He and 1H images were acquired in a synchronised scan during inhalation providing regional gas flow with spatially and temporally registered lung anatomy motion. Lung ventilation is very fast (air reaches lung periphery within 1s) and demands fast sequences that can capture the rapid flow of 3He gas in lung airways. Compressed Sensing (CS) was used to assess the feasibility of accelerated synchronous 3He/1H acquisition.

Keywords

ability accelerated acceleration achieved achieving acknowledged acquiring acquisition actual additional airways allows anatomical anatomy apparatus apparent applications assess assessment asthma asymmetric birdcage body capture clear coil combined compressed compromise coronal decreasing demands depending detect detuned diaphragm disease dose dual dynamic dynamics either elliptical encode encoded example exchange fashion fast feasibility features flow fold frame frames frequency fully functional funding gases give giving healthy helium help inhalation inhaled insight intensity interleaved investigated kingdom lung major mapping materials mixed mode motion mutual network nucleus offer organ parametric pattern patterns performance periphery physiology pixel possibility processes projection proton prototype providing quadrature quality random rapid reaches readout receive reconstructed reconstruction reduced regional registered registration related resolution respectively sampled sampling schedule sensing separately simultaneous simultaneously slice slow software space spatial spatially spin step strategy successive switching synchronous system temporal temporally transmit trapping unique upon ventilation volume volunteers wall whole wild