Meeting Banner
Abstract #1284

Age Related Perfusion and Vascular Permeability Characteristics of Liver Measured by DCE-MRI

David H. Gultekin1, Nancy E. Kemeny2, Lawrence H. Schwartz3, Mithat Gonen4, Michael I. D'Angelica5, Peter J. Allen5, Yuman Fong5, Leslie H. Blumgart5, Ronald P. DeMatteo5, William R. Jarnagin5

1Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, United States; 2Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, United States; 3Radiology, Columbia University, New York, NY, United States; 4Epidemiology-Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, United States; 5Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, United States

Age related changes in perfusion and vascular permeability characteristics of the liver tissue have been investigated using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). Correlation statistics are performed between the age and several DCE-MRI parameters for subsets of gender and type for a group of primary liver cancer patients.

Abstract PDF

Keywords

aging although analyzed angelica anti application array arterial assessment biostatistics blood bolus cancer cancers carcinoma cause cellular channel characteristics chemotherapy choice coefficients coil combined compartmental concentration constant contrast corrected correlated correlation correlations curve decrease degrees diagnosis dose enhanced enrolled epidemiology extra female flow fractional function gems gender hepatic important improve infusion injected input intervals investigate investigated investigation lance limited liver location made male maps materials measure measured medicine memorial model monitoring motion much often overall patient patients peak perfusion permeability peter presence pretreatment primary radiology receiving regional related respiratory response scanned space subset subsets surgery table therapy tissue tissues transfer treatment trials tumor tumors type variable variation vascular volume