Meeting Banner
Abstract #1226

Free-Breathing 3D Water-Fat Separation and R2* Mapping in the Heart

Valentina Taviani1, Diego Hernando1, Ann Shimakawa2, Jean H. Brittain3, Kevin M. Johnson1, Karl K. Vigen1, Scott B. Reeder1, 4

1Department of Radiology, University of Wisconsin, Madison, WI, United States; 2Global MR Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; 3Applied Science Laboratory, GE Healthcare, Madison, WI, United States; 4Department of Medical Physics, University of Wisconsin, Madison, WI, United States

R2* mapping in the heart is important to quantify myocardial iron concentration as well as for accurate water-fat separation. However, R2* measurements in the myocardium are hampered by severe susceptibility variations due to the presence of tissue-air interfaces and deoxygenated blood in epicardial veins. In this work we propose a 3D free-breathing technique for water-fat separation and R2* mapping in the heart and we compare our 3D free-breathing approach with a previously reported 2D breath-hold technique. Both phantom experiments and preliminary data in healthy volunteers showed that the 3D free-breathing technique greatly reduced susceptibility-induced variations in R2*.

Abstract PDF Poster PDF

Keywords

account accurate achieve acquisition acquisitions applied arteries assuming asymmetry axial axis back band body breath breathing card cardiac channel coil comp compensate complete confirmed contrast coronary corrected detection distribution echoes effective erroneous especially essential estimation evaluated every fatty fifty free gating gave global gradient gratefully healthy heart hold holds ideal included induced inferior intensities interleaved interleaves intervals iron jean laboratory leading least long maps masses matrix medical meters minute minutes motion myocardial myocardium navigator needed oiled pared park plan played port preparation presence propose proposed pulse quired rapid read receive receiver reduced reeder reformats resolved respectively respiratory science segmented sense separated separation shim short significantly slice slices spatial spectral strategy supp suppression susceptibility thick thin tissue uniform variation variations veins view volunteer water watter whole width