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Abstract #1158

About the Performance of Multi-Dimensional Radial Self-Navigation Incorporating Compressed Sensing for Free-Breathing Coronary MRI

Gabriele Bonanno1, 2, Gilles Puy3, 4, Yves Wiaux3, 5, Ruud B. van Heeswijk1, 2, Matthias Stuber1, 2

1Department of Radiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Vaud, Switzerland; 2Center for Biomedical Imaging (CIBM), Lausanne, Vaud, Switzerland; 3Institute of Electrical Engineering, cole Polytechnique Fdrale de Lausanne (EPFL), Lausanne, Vaud, Switzerland; 4Institute of the Physics and Biological Systems, cole Polytechnique Fdrale de Lausanne (EPFL), Lausanne, Vaud, Switzerland; 5Institute of Bioengineering, cole Polytechnique Fdrale de Lausanne (EPFL), Lausanne, Vaud, Switzerland

A novel image-based respiratory self-navigation method was developed for free-breathing coronary MRI. Under-sampled radial sub-images are acquired on a beat-to-beat basis, non-linear reconstruction is performed, and motion parameters are extracted for direct motion correction. In a first step, the new algorithm was optimized and evaluated using a numerical simulation of a moving heart. Subsequently, the performance was quantitatively ascertained in an in vivo study that included 12 healthy adult subjects where it was objectively demonstrated that self-navigation incorporating compressed sensing is a powerful tool for motion artifact suppression in radial coronary MRI.

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Keywords

accelerated accounts acquisition acquisitions adult adversely affected albeit among anatomy applied approaches artery artifacts ascertained avoiding basis beat better bioengineering biomedical blood borrowed breathing bubble cardiac chest collected combined comparing compensation compressed computer concept consistent consistently coronary corrected correction correlation corrupted cycle delineation described developed diameter diaphragmatic dimensional directly displacement dotted efficiency estimation expense explained exploited exploits extracted fact fold free furthermore gating healthy heart highest human humans identical implemented implementing improved in vivo incorporates incorporating individual institute interleave interleaves introduce leads linear liver long materials matrix methodology mimics motion moving multidimensional myocardium navigated navigation navigator navigators numerical optimal overall performance phantom physics pipeline plan pool prep processing projection projections quality radial reconstructed reconstruction reduced remained representative residual respiratory response retrospectively sampled samples scanner scanning self sensing sharpness significantly simulated simulation space static still strategies streaking structures student subjects subsequent substantially suffer superimposed targeted tool triggering trio unchanged variation vessel wall window yielded