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Abstract #1017

Prediction of Outcome in Cerebellar Infarction by Diffusion MRI

Zahari Tchopev1, Jiachen Zhuo1, Josh Betz1, Rao Gullapalli1, Kevin N. Sheth2

1Magnetic Resonance Research Center, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, United States; 2Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, United States

Early identification of patients at risk for neurological deterioration following stroke remains a challenge. Retrospective analysis on 28 patients with cerebellar stroke was performed to identify whether the combined information from cerebellar lesion volume defined on DWI-MRI, cerebellar ADC values, and the NIH stroke scale score would serve as prognostic indicators of clinical outcome. Logistic regression revealed relative cerebellar lesion volumes to be significant predictors of poor outcome, even when controlling for age, NIHSS score, and hours to scan. On average, patients with 30% involvement of the cerebellum (~41cc) were determined to have a poor outcome.

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Keywords

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