Meeting Banner
Abstract #0965

Iron Quantification in the Putamen Using Susceptibility Maps

M. Ayaz Khan1, 2, Naveed Bawany3, Rosemary Parker2, Cynthia Tinajero2, Jaladhar Neelavalli4, E. Mark Haacke4, 5, Rong Zhang1, 2

1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States; 2Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX, United States; 3Biomedical Engineering Department, Wayne State University, Detroit, MI, United States; 4Radiology, Wayne State University, Detroit, MI, United States; 5Biomedical Engineering Department , Wayne State University, Detroit, MI, United States

Iron accumulation is basal ganglia is associated with aging. In this study susceptibility maps were generated to quantify iron in brain structure in wide range (21-69) of subjects.

Keywords

absolute address adults advance aged aging applied artifacts assess axial axis best biomedical brain called close collected complex confirm considered consistent content contrast correlation corresponds defined dependent deposition deposits detected detection developed distribution draw drawing efficacy engineering enhance environmental even exercise explore filter filtered final findings flow fluorescence free frequency furthermore future generated ghosting gradient health healthy hospital human independent initial institute internal interventions inverse involved iron isotropic issues khan larger linearly longitudinal mapping maps mark matrix measure measured medical medicine middle modalities multiplied near noise older orientation parker pass pilot positive potential presbyterian presence prevent previous processing proportional quantification quantify radiology recent recently reconstruct reconstruction reduce regional regularization regularized relies remove resolution restricted rosemary sample sense shape singularities slice slow southwestern space spatial spin steps structure studies subjects susceptibility swim systems taken threshold thresholding thresholds tissue tissues training transform trend units vascular veins vessels warranted whole wide years young zero