Regional Assessment of Magnetization Transfer Ratio in the Mouse Brain - Tracking Myelin Change in a Model of Toxic Demyelination.

Keywords

according acquisition activity adding agreement anesthetized animal animals approved assessed assessing assessment authority automatic bergen blinded blue body bore brain central chow clinical comparing competence complete conducted consecutive content control coronal corpus debris deep detect detected detecting determining developed disease disorders distinguish dynamics early efficacy eight embedded ending enhancement evaluation experienced explanation exposed exposure failure fast feasible female five fixated flash foremost formalin frequency full functional gender generated gradient gray guided guidelines healthy horizontal hospital important in vivo independent induced integrity investigate known laterally loss magnet magnetization maps matched matrix medicine mice minutes model monitored monitoring mouse nervous neurology observer operator paraffin patients period periods possibility preparation promising pulse quantitative rapid rare reduction regional relation resolution respectively respiratory sacrificed samples scanned scanning sclerosis scored sections segment segmentation segmented semi semiquantitative shaped shot spin stained structural superimposed system temperature temporal thereafter throughout tool toxic tracking transfer treatment viable violet week weekly weeks whereby whole