Study of Prefrontal Cortical Metabolism in Stressed and Resilient Mice in Social Defeat Model of Depression

Keywords

abnormal abnormalities acids activity administered aggressive although amino anesthetized animal approved behavioral believe biology blood brain cellular cerebral choline clear clinical committee complex concentration control cortex cortical council days decreased defeat deficit depressed depression depressive determined disorder disorders displayed drug energetics enrichment ethics evaluated events evidence extract extracted fasted flow fluid frozen function funding glucose glutamate hypothesized important induced industrial institute interaction investigated investigations labeled labeling life like major male materials mechanisms metabolic metabolism metabolites mice might model molecular month neuropsychiatric often overnight paradigm pathways patients percent phenotype plasma plays preference protocols psychosocial reasons recorded reduce reduced reduction repeated rescuing resilient responsible role scientific severe social spectrometer spectroscopy spectrum still stressed strong subjected sucrose suggest suggests supported symptoms syndrome system threatening tissue together treated unperturbed urethane