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Abstract #0556

Initial in vivo Evaluation of a Breast-Specific MRgHIFU System

Allison Payne1, Robb Merrill1, Emilee Minalga1, Nick Todd1, Joshua de Bever2, Erik Dumont3, Leigh Neumayer4, Douglas Christensen5, 6, Robert Roemer7, Dennis Parker1

1UCAIR, Department of Radiology, University of Utah, Salt Lake City, UT, United States; 2Department of Computer Science, University of Utah, Salt Lake City, UT, United States; 3Image Guided Therapy, Bordeax, France; 4Department of Surgery, University of Utah, Salt Lake City, UT, United States; 5Department of Electrical and Computer Engineering, University of Utah, Salt Lake City, UT, United States; 6Department of Bioengineering, University of Utah, Salt Lake City, UT, United States; 7Department of Mechanical Engineering, University of Utah, Salt Lake City, UT, United States

In Vivo results show the potential of a new breast-specific magnetic resonance guided high intensity focused ultrasound system to treat and manage breast cancer. The system comprised of a laterally-shooting phased array transducer with an integrated 11-channel RF-coil system was evaluated in an in vivo rabbit model. The presented results show the volumetric thermal dose accumulated in the ablated tissue with accompanying post-treatment T2w images and gross histology results.

Keywords

ability ablate ablated ablation access accuracy acoustic anesthetized animal aperture approx array arrow axial axis beam become beneficial bioengineering body breast care cations channel city coil column committee comp compatible coronal curve cylinder delivery design developed device disadvantage distance dose east effective effectively efficacy electrical elements engineering evaluation features flexibility focal focus foundation grant gross guided heating hind histological histology hooting house improved in vivo include indicate indicates initial integrate lake laterally legs lesions localize loop lumbar management mens merged model monitor mounted muscle near next nick nous oblique oriented parker path pended phantoms pine post potential power previous procedure providing qualitative rabbit radiology repeated ruler safety salt science setup slab slice slices smaller solution spacing spherically spine spot steering studies suitable surrounds symposium system target temperature therapy thermal tissue tissues tool trajectory treatment trio ultrasound valuated volume white wide window zone