Real-Time Metabolic Probe Into Non-Alcoholic Fatty Liver Disease with Hyperpolarized Carbon-13

Keywords

abnormality access according acid activity addition advanced alanine alcoholic alkaline alternative analyzed animals assessed attributed axial better bicarbonate biochemical biomolecules biopsy blood body carbon chow cirrhosis collected comp comparative condition consequent consortium containing contributing conversion corroborated currently defined detection determined developed diabetes diagnosis diet diets disease diseases disorders dissolved doped elevated encompasses enhanced established exhibited expected exploring fasted faster fatty fibrosis fitted flux free glucose grading heated heavier hepatic histology illustrates immediately implemented in vivo increasing increasingly indicate indicative infusion initial injected intervention intolerant intravenous invasive involves lactate liter liver manage manner measured metabolic metabolism metabolite metabolites mice model monitoring mouse need needed onset package paraffin peaks polarization polarizer pools potential pressurized prevalent probe production prognosis progression quantification quantify real relies reveals sample samples scanned selective serum serve seven severity significantly slice sodium solution spectra spectrum stage staging stained statistics student subsequently sweep system tail tailed tolerance transformation upon vein weeks width yield