Steven Baete1, Gene Cho1, 2, Eric E. Sigmund1
1Center for Biomedical Imaging, Dept. of Radiology, NYU Langone Medical Center, New York, NY, United States; 2Sackler Institute of Graduate Biomedical Sciences, NYU School of Medicine, New York, NY, United States
This abstract describes the implementation of a rapid method to acquire a full diffusion tensor in on a clinical scanner. The method is named the 3D multiple modulation multiple echo diffusion tensor acquisition technique (MEDITATE). MEDITATE employs four rf-pulses and a pattern of diffusion gradients on three gradient axes to encode a train of 17 echoes with different diffusion weightings and directions. The resulting diffusion weighted signals can be used to estimate DTI parameters as demonstrated in a fibrous phantom. This sequence may be useful in clinical applications requiring time-sensitive acquisition of DTI parameters such as dynamical DTI in muscle.