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Abstract #0054

Validation of Bound & Free Water Measurement Using Bi-Component Analysis of UTE Images of Cortical Bone

Jiang Du1, Shawn Grogan2, Won Bae1, Christine B. Chung1, Darryl DLima2, Graeme M. Bydder1

1Radiology, University of California, San Diego, San Diego, CA, United States; 2Scripps Clinic, San Diego, CA, United States

 

Keywords

able accurate achieved agreement allow allowed allows another applicable applications applied assess bone bound bovine chemical clinic clinical coil collagen complete component components concentration concentrations consistent constant content contents contributes correlated correlation cortical days decay decreased degrees detect detectable determined distinct distribution divided dried dropped drying equilibrium error excellent exchange excitation expected experiment exponential external extremely fairly fitting five focus fraction fractions free future gain gill gradually gravimetric heavier hours human hydroxides in vivo inch independent indicate indicating induction integrating intensities investigated isotope laboratory limited lipid long loss materials matrix measure measured measures methylene mineral minimize minutes much organic origin osteoporosis oven participate percent phantom placed populations porosity probably properties proton pulse quantified quantify radiation radioactive radiology ranging reached recently rectangular reliably remains residual respectively room samples scanner scanners segments selective sequential series short slice slower source sources spectroscopy stages subject subjected suggesting suggests surface temperature ultrashort undetectable validate validation volume water