Altered Functional Network in Different Stage of Patients with Parkinson's Disease: Evidence from Resting-State FMRI

Keywords

abnormal activity aims alteration alterations altered amplitude analyses applied avoid bilateral blood blue bold brain cerebellum characterize characterized china circle clinical coefficient cognitive complementary complex confounding control controls corrected correlation correlations cortex decreased degeneration demographic dependent determined disease disorder distributed divided dong duration dynamically early electric enrolled even examination examine excite exploratory extracted females fluctuations frequency frontal function functional fusiform general gong gradient handed healthy hospital hyperactivity included inclusion indicate inferior input investigate late lobe males manifestations maps meanwhile mediating medication mental middle mini motor negative network neural neurology neurons occipital parietal particularly patient patients pattern patterns people planar plot positive post previous progressive radiology rating recent recruited reflect regional relationships remains republic requirements rest resting revealed scale scanned scatter score scores significantly slowly software song spatially spontaneous stage stages statistical still structure studies subgroups subjects subsequently symptomatic system systems table tailed tang temporal thirty thought threshold unclear unified west years