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Abstract #4491

A Qualitative and Quantitative Assessment of Real-Time Cardiac Functional Imaging Using Through-Time Radial GRAPPA

Vidya Nadig1, Victoria Yeh2, Gunhild Erstad Aandal3, Prabhakar Rajiah3, Trevor Jenkins4, Abdus Sattar5, Mark A. Griswold3, 6, Vikas Gulani, 67, Robert Chapman Gilkeson3, Nicole Seiberlich6

1Cardiology, MetroHealth Medical Center at Case Western University, Cleveland, OH, United States; 2Case Western Reserve University School of Medicine, Cleveland, OH, United States; 3Dept. of Radiology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, United States; 4Cardiology, University Hospitals of Cleveland, Cleveland, OH, United States; 5Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, United States; 6Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 7Dept. of Radiology, Case Western Reserve University, Cleveland, OH, United States

Temporal resolutions <50 ms can be achieved using through-time radial GRAPPA for CMR, obviating need for gating or breathholding. In this study, 41 subjects underwent functional cardiac imaging using standard breathhold cine and real-time imaging (with through-time radial GRAPPA). Bland-Altman analysis of LVEF from the two methods showed 39/40 of measurements within 95% limits of agreement, and the mean difference was -1.9%. Radiologists rating showed >90% of qualitative parameters for both methods were in the excellent or good visibility range. This indicates that real-time imaging could replace breathhold cine, and be used for patients with arrhythmia or difficulty breathholding.

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Keywords

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