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Abstract #4484

Evaluation of Highly-Accelerated Non-Gated Cardiac Cine MRI in Tachycardia

Elwin Clark Bassett1, Edward V.R. DiBella2, 3, Eugene G. Kholmovski2, 3, Brent Donald Wilson3, Christopher J. McGann3, Nassir F. Marrouche, 34, Daniel Kim, 23

1Physics, University of Utah, Salt Lake City, UT, United States; 2UCAIR, University of Utah, Salt Lake City, UT, United States; 3CARMA, University of Utah, Salt Lake City, UT, United States; 4Internal Medicine, University of Utah, Salt Lake City, UT, United States

The current gold standard for imaging left ventricular function is electrocardiogram gated cine MRI with balanced steady-state of free precession imaging, which provides excellent myocardium-to-blood contrast. However, it yields non-diagnostic quality images in patients with arrhythmias because data acquisition is synchronized to cardiac rhythm and spread over multiple heart beats. We have developed an 8-fold accelerated non-gated cardiac cine sequence using k-t SPARSE-SENSE. We will evaluate this pulse sequence for assessment of cardiac function in the context of tachycardia, where high temporal resolution is critically important for diagnostic confidence.

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Keywords

accelerated accuracy accurate acquisition agreement analyzed anesthesia animals arrhythmias artifacts assessment atrial axis balanced beats better bland blood breath breathing cardiac cardiology cause chronic cine city combination compressed conducted conducting confidence considered context contrast critically degrees details developed diagnostic dogs dysfunction ejection electrocardiogram enables error evaluate evaluation examination excellent experimental fibrillation fibrosis field fold force fraction free function gated goat goats gold good heart highly hold impact implementation important internal intervals irregular lake longitudinal matrix medicine middle minimize minute myocardial myocardium needed normalized patients physics physiological precession precision pulse quality quantification radiology randomized ranging relationship relatively relevant representative resolution respectively respirator rhythm rigorous root salt segments sense sensing setting short sinus slice society software sparse spread square steady summarized sync synchronized system table tachycardia task temporal trio variation ventricular view yielded yields zero