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Abstract #4325

Optical Flow Analysis on Undersampled Radial Acquisitions for Real-Time Tracking of the Pancreas in MR Guided Radiotherapy

Bjorn Stemkens1, 2, Rob H. N. Tijssen2, Cornelis A.T. van den Berg2, Jan J.W. Lagendijk2, Chrit T.W. Moonen3, Mario Ries3, Baudouin Denis de Senneville3, 4

1Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands; 2Department of Radiotherapy, UMC Utrecht, Utrecht, Netherlands; 3Image Science Institute, UMC Utrecht, Utrecht, Netherlands; 4IMB, UMR 5251 CNRS/University Bordeaux 1/INRIA, Bordeaux, France

MR-guided radiotherapy opens up the way to track organs during radiation. Tracking using optical flow has been successfully applied on EPI images for HIFU treatments. Geometrical distortions make EPI sequences unsuitable for radiotherapy purposes. Therefore, the feasibility of optical flow on undersampled radial acquisitions is investigated. Simulations and 2D in vivo scans are used to find the tradeoff between artifacts, temporal resolution and field-of-view. In addition multi-slice in vivo data is acquired to gain insight in the 4D motion of the pancreas for real-time position verification during radiation.

Keywords

abdomen accumulation accurate accurately achieve acquisition acquisitions adaptation although amounts amplitude artifacts assess assessed axis become belt berg biomedical body breathing calculations capture cardiac cause characterize characterizes cine comparable component concern contributions convenience conventionally coronal correlation cost courses described deviations displacement distortions dose encircled engineering error errors evaluate example fashion fast field fields findings flow fold fractionated free frequencies frequency full fully furthermore future gain gated geometrical global guided harmonics healthy horn implies in vivo include induced interleaved investigate margins measure mimic minimal motion needed noise optical optimal organs orthogonal pancreas pancreatic periodic pilot positioned posterior power pressure previous principal procedures prominent promising pronounced quantitative quasi radial radiation radiotherapy real reconstructed recorded reduce reduced registered relatively residual resolution respiratory sampled scanned scanner science series served simulations slice slices smaller spectra spectrum spokes streaking subject subjects successfully sufficient suggests suitable surrounding target temporal track tracking treatment treatments turbo vector vicinity view volume whereas white