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Abstract #4318

Intra-Arterial MRA Based Roadmapping for Magnetically-Assisted Remote Control Catheter Tracking

Alastair Martin1, Prasheel Lillaney1, Maythem Saeed1, Fabio Settlecase2, Leland Evans3, Mark Wilson1, Steven W. Hetts3

1Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States; 2Dept of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; 3Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States

An imaging technique is presented for guiding magnetically-assisted remote control (MARC) catheters with MR methods. The technique is based on establishing an initial roadmap angiogram via intra-arterial delivery of Gd-based contrast. This mask is subsequently subtracted from later dynamic acquisitions, revealing local arterial anatomy after washout of the contrast injection. By utilizing thick 2D slices and keyhole methods high temporal resolution can be achieved in combination with low contrast requirements and low SAR. This methodology is demonstrated in a swine model where the artifacts produced by MARC catheter activation are negated, improving visualization of arterial anatomy during navigation.

Keywords

achieve acquisition acquisitions activated activation advantages allows alternate anatomy applied applying appreciated around arrows arterial artery artifact assisted assure background balanced began beginning biomedical blood brief carotid catheter catheters clinical conductive contain contrast control create created creates deflection deflections dept described digital dilute dimensions distances disturbance dose dynamic ease elements employed enable established evident exceptionally fact field flow gadolinium generate generated gradient health highlight immediately implications importantly include infusions initial injected injection injections intra iterative just keyhole length local locally long magnetically makes mark mask medium minimal mode model moderately moments necessary objects obliterated obscure obscured obscures outset passive period permits permitted permitting position practical practices previously produce produced protocol radiology rapidly refresh remote requires resolution retained reveal running scaled sciences selected selective simple slice smaller spoiled steerable steering structures subsequent substantial subtracted subtraction susceptibility swine temporal thick throughout tortuous track tracked tracking transiently typically vascular vessels visualization washed washes yellow