Meeting Banner
Abstract #4307

Prediction of Hypothermia During Radical Prostatectomy by Using an Endorectal Cooling Balloon: A Bioheat Simulation Based on 3D Pelvic Structure Segmented on Prostate MRI

Peter T. Fwu1, 2, Jeon-Hor Chen3, Yuting Lin1, Wei-Ching Lin4, Po-Jung Tseng1, Eddie Lin1, Min-Ying Su1, 2

1Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, CA, United States; 2Department of Physics and Astronomy, University of California, Irvine, CA, United States; 3Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California Irvine, Irvine, CA, United States; 4Department of Radiology, China Medical University Hospital, Taichung, Taiwan

Regional hypothermia through endorectal cooling balloon (ECB) is shown capable of minimizing the long term urinary incontinence and sexual dysfunction. However, there is no tool to optimize ECB setting to reach the desired protective cooling effect. A bioheat simulation equation based on each individual patients own 3D anatomy is developed to model the cooling process by using the finite element method. Using this model, we evaluated the impact of geometrical distance from ECB, the balloon temperature, and the presence of blood. In addition, the effect of arterial ligation to decrease the blood perfusion to NBV was also evaluated.

Keywords

abbr abnormality abundance addition adjusting affect affected alleviated among analyzed anatomic anatomy anterior application applied arterial astronomy augment away background balloon beneficial bladder blood blue boundary china closest cold colors comparing compartments compute conditions consideration considered constantly continence cooled cooling course covers currently decrease difficult dist distance dynamics effectively element equilibrium especially evaluate every feasible finite five function functional gland gradual heat heating hour hypothermia illustrated improve improved incontinence incorporated individual induced injury known life ligation light long model neck nerve optimize outcomes patient pelvic perfusion physics planning plexus positive post posterior prediction prostate quantitative radical radiological reach reached received reconstructed reconstruction recovery rectal regain related removal required saline sciences screening segmentation segmented selected sexual shade significantly simulated simulation slice solid solution sphincter starts studies subject subjects successful supplied supply surface surgery surrounding table take temperature term thermal tissue tissues tool toward transfer treatment turning urethra urinary venous volume warm years