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Abstract #4165

Reproducibility Improvement of ADC Measurement on Left Lobe of Liver

Tetsuo Ogino1, Toshiaki Miyati2, Marc Van Cauteren3, Tomohiko Horie4, Yutaka Imai5

1Healthcare department, Philips Electronics Japan, LTD, Minato-ku, Tokyo, Japan; 2Kanazawa University, Kanazawa, Ishikawa, Japan; 3Philips Healthcare LTD, Minato-ku, Tokyo, Japan; 4Dept. of Radiology, Tokai University Hospital, Isehara, Kanagawa, Japan; 5Radiology, Tokai University, Isehara, Kanagawa, Japan

With conventional respiratory triggering DWI, left lobe of liver ADC is artificially elevated by cardiac motion and suffer from poor reproducibility. The combined method of PPU and respiratory navigator slice tracking on 3.0T scanner is proposed. The method eliminating the cardiac motion effect reduced left/right lobe normal parenchyma ADC difference times to 1.01 from 1.7 times of conventional respiratory triggering method. 20 slices were acquired 40-80 sec depending on subject. It allows uniform and reproducible ADC measurement in clinically feasible scan time.

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Keywords

abdominal accuracy acquisitions actual additional affects allows among another apparent apparently appeared appears artificially attenuation beats blur body bottom breath breathing cancer cardiac cause caused causes certain clinical clinically combined combining compensates compensation constant correct cover deformation delay dept detection diffusion early ease electronics elevated eliminate employed equal expected feasible free frequently gradient healthy holding hospital implemented improve improved improvement improves index infer insignificant inter issue issues japan larger limited liver lobe lobes location longer loss magma major matrix measured motion navigator nominal notably occasionally peripheral poor poster posterior preferred prior prolongation promising proposed pulsation pulse radiology recent recently reduced reducing repeated repeats reproducibility respect respiratory response reversal scanner selection sense sensitive served severe shot significantly slice slices smaller statistically studies subject subjects suggests suppressed suppression system table therapy tracking traditional trigger triggering twice uniform unit variance volunteers whole widely