Meeting Banner
Abstract #4110

Respiratory 3D Cine MRI of Upper Airway Dynamics in Obstructive Sleep Apnea

Mark E. Wagshul1, Sanghun Sin2, David M. Wootton3, Michael L. Lipton1, 4, Keivan Shifteh4, Raanan Arens2

1Radiology, Gruss MRRC, Albert Einstein College of Medicine, Bronx, NY, United States; 2Pediatrics, Montefiore Medical Center, Bronx, NY, United States; 3Mechnical Engineering, The Cooper Union for the Advancement of Science and Art, New York, NY, United States; 4Radiology, Montefiore Medical Center, Bronx, NY, United States

Retrospective, 3D cine imaging using respiratory gating has the ability to demonstrate high resolution, dynamic imaging of the upper airway. This is an important technique for studying airway motion in obstructive sleep apnea syndrome (OSAS), and will ultimately allow accurate modeling of upper airway motion for designing optimal treatments. Cine imaging was used in 24 adolescents being evaluated for polycystic ovary syndrome, a condition with high OSAS prevalence. In two OSA patients with severe obstruction of the upper airway, the technique allowed visualization of asynchronous airway motion, compared to mostly synchronous airway motion in non-OSAS patients.

Keywords

ability abrupt abruptly activation adolescent adolescents affecting ages airway allow allows although amplitude another appreciated appropriate approved arrow arrows asynchronous axial beginning benefit best breath breathing cine clearly cluster cognitive collected college compliance conditions confirmed constant constriction contrast covering cross cycle done dynamic dynamics earlier either engineering ensures evaluated expiration extent extract facilitated flow funded gating girls growing health host important independent indicate indicates indication inspiration institutes interactions interventions introduced isotropic leads length likely linked local loss made majority mark measure medical medicine monitor motion nasal national near neuromuscular obesity obstruction obstructive occurring occurs ovary participation patient patients peak physiological plots position precisely prevalence prior problem problems public quantitative radiology rapidly reconstruction remain resolution respiratory retrospective retrospectively revealed reveals rising roughly science segmentation sense severe shot site sleep slice slices social subject subjects surface synchronous syndrome system thought throughout tidal timing tissue transform turbo unclear union upper varying viewing wakefulness yellow