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Abstract #4096

Toward an Improved Quantification of Adipose Tissue Components: T1 Assessment in Morbidly Obese, Non-Obese NAFLD and Healthy Lean Subjects at 1.5 T

Nikita Garnov1, Henriette Bertram1, Gregor Thrmer1, Thomas Karlas2, Tatjana Schtz3, Thomas Kahn1, Harald Busse1

1Diagnostic and Interventional Radiology, Leipzig University Hospital, Leipzig, Germany; 2Internal Medicine, Neurology and Dermatology, Leipzig University Hospital, Leipzig, Germany; 3Visceral, Transplantation, Thoracic and Vascular Surgery, Leipzig University Hospital, Leipzig, Germany

T1 relaxation times of adipose tissue have often been used to correct for T1 effects in the quantification of liver fat content. These values, however, were derived in healthy lean subjects and may therefore vary from those in obese patients. This work determines T1 relaxation times at 1.5 T in subcutaneous and visceral adipose tissue in morbidly obese subjects and patients with NAFLD. The results showed that the T1 values in adipose tissue of both obese and lean NAFLD patients can be significantly shorter than those in healthy controls.

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