Xiaodong Zhong1,
Yevgeniya M. Lyubich2, Timothy DeVito3, Saurabh Shah4,
Jack Knight-Scott2
1MR
R&D Collaborations, Siemens Healthcare, Atlanta, GA, United States; 2Department
of Radiology, Children's Healthcare of Atlanta, Atlanta, GA, United States; 3Siemens
Canada Limited, London, Ontario, Canada; 4MR R&D
Collaborations, Siemens Healthcare, Chicago, IL, United States
In this study, we examined the robustness of three automated shimming techniques for single-voxel spectroscopy at 3T: FASTESTMAP, GRESHIM, and a standard vendor-offered product. Quantitative results across multiple brain regions over twelve participants anterior and posterior cingulate, centruum semiovale, and temporal lobe along the sylvian fissure showed that FASTESTMAP and GRESHIM provided the robustness and reliability necessary for quantitative assessment of spectra, while the vendor-supplied shimming technique had the poorest performance. Our results show that FASTESTMAP and GRESHIM greatly improve the reliability of clinical spectroscopy