Meeting Banner
Abstract #3947

A 16 Channel Cardiac Array for Accelerated Hyperpolarised 13C Metabolic Imaging on Pigs at 3T

Titus Lanz1, Markus Durst2, 3, Matthias Mller1, Francesca Frijia4, Giulio Govanetti5, Luca Menichetti5, Massimo Lombardi4, Jan Henrik Ardenkjaer-Larsen6, 7, Rolf F. Schulte2

1Rapid Biomedical, Rimpar, Germany; 2GE Global Research, Munich, Germany; 3Technical University Munich, Munich, Germany; 4Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy; 5Institute of Clinical Physiology of CNR, Pisa, Italy; 6GE Healthcare, Copenhagen, Denmark; 7Danish Technical University, Copenhagen, Denmark

We show a setup for doing 13C imaging on hyperpolarised media in pigs on a clinical 3 T MR system. A 16 channel 13C Rx array is combined with a Tx birdcage, allowing the MR system's body coil for 1H imaging. Due to the low frequency the array is not sample noise dominated, but allows accelerated 13C imaging which is essential for efficient usage of the hyperpolarised magnetisation. First results of metabolic imaging on the pig heart are shown.

Keywords

accelerated accomplish achieving acquisition active actively allowing allows application applications array arrays audience available axis baked better biomedical birdcage blood board body cable cardiac channel circuit circuitry clinical coil coils combined common community composed contains coupling danish decoupled decoupling delay derived design detuning developed diode diodes displaying done drastically efficient electrical element elements enable encoding essential evaluate even fairly farm fast final fixed flexibility flexible foam frequency funding gets getting goal hardware healthy heart hence heretofore housing human humans improve included injecting inner interleaves involved lactate length limited long made mainly makes male manually match matched matching mechanisms media metabolic metabolism metabolites muscle myocardium necessary needs noise nuclei overall parts passive performance physiology pigs possibility potential preamplifier printed reason receive reconstruction replenishing requires resolved resonating resonator safety scanners sense setup shifters short since solution still substances sufficient symmetric system target technical technology thin transferring trap traps tune tuning unloaded view visible