Hyperpolarization of Drugs Using Signal Amplification by Reversible Exchange (SABRE)

Keywords

achieve achieved acquisition advantages amplification appropriate audience banner bath beyond bind binds bound brain bubbling catalyst catalyzing cell chamber chem chemical chemistry clinic comparing complex concentrations controlled conversion cooling coupling couplings daily depend dependence determined distribution drug drugs easy electromagnet employs enabling enhanced enhancement enhancements equals equilibrium exchange experimentally fast field fields flow form frequency functional generated hydrogen hydrogenation immediately implementation improved in vivo increasing induced institute investigated iridium isomer isomers jean johns kingdom lane limited loaded magnet manner medicine metabolism metal methanol mixing mixture molecule monitoring need networks nuclear observing optimal optimized organic outside para peter physicists plus pneumatically polarization polarize polarized polarizer possibility prefers preparing process product protons pure radiology real recently released require required residence returned reversible sample scalar school science sensitivity several shorter simultaneously solution spectra spectrometer spin stabilizes straightforward stray strong structure subsequently substrate takes target temperature thermal transferred treating treatment tuberculosis tumor tumors tunable underneath unsaturated water