Gary R. Stinnett1,
Minjung Cho2, Huigang Zhu2, Pedersen E. Steen1,
Christeen Beeton1, Vicki L. Colvin2, Robia G. Pautler1
1Molecular
Physiology and Biophysics, Baylor College of Medicine, Houston, TX, United
States; 2Chemistry, Rice, Houston, TX, United States
We have developed novel gadolinium oxide contrast agents with an R1 three times higher than Magnevist in a 9.4 T MRI. These agents were used to label macrophages resulting in labeled cells significantly brighter than non-labeled cells.