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Abstract #3841

Measurement Precision of Contrast Agent with R2* (Magnitude) and Quantitative Susceptibility Mapping (Phase)

Hongchen Wang1, Xavier Matre1, Jean-Pierre Ruaud1, Luc Darrasse1, Ludovic De Rochefort2

1Imagerie par Rsonance Magntique Mdicale et Multi-Modalits (UMR8081) IR4M, CNRS, Univ. Paris-Sud,, Orsay, France; 2Univ Paris-Sud, Orsay, France

Apparent transverse relaxation rate R2* and magnetic susceptibility χ are distinct measurable parameters that can be used to quantify paramagnetic and superparamagnetic materials. R2* mapping requires several echoes times in a gradient-echo scan and is based on the analysis of signal amplitude decrease. Magnetic Susceptibility mapping uses field mapping that can be measured from the same multi-echo dataset using phase images. Here, phantom experiments are done to compare the precision of R2* and susceptibility methods for quantifying contrast agent concentration.

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Keywords

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