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Abstract #3670

Selection of Coils, Sequences and Scan Parameters for Non-Human Primate Brain Imaging

Michael H. Buonocore1, 2, David G. Amaral3, Gerald J. Sonico2, Jeff Bennett3, Martin Styner4

1Radiology, UC Davis, Sacramento, CA, United States; 2Imaging Research Center, UC Davis, Sacramento, CA, United States; 3Psychiatry and Behavioral Sciences, UC Davis, Sacramento, CA, United States; 4Psychiatry and Computer Science, University of North Carolina at Chapal Hill, Chapel Hill, NC, United States

This abstract reviews the process of selecting RF coils, pulse sequences and scan parameters for structural and functional brain imaging of non-human primates (NHPs). Compared to these factors in human imaging, the smaller size of the NHP brain, desire for high spatial resolution, and ability to scan for longer durations without head motion, lead to selections that are uncommon in human imaging yet generate NHP images with high spatial resolution, tissue contrast, and SNR. The unique characteristics of NHP imaging provide opportunities for protocol optimization that are not practical, or not available, for human imaging protocols.

Keywords

achieve acquisition adult advanced agreements anesthesia anesthetized anterior available axial band bandwidth behavioral best blood bold bordering bore brain bulk calibration care channel characteristics clamshell coil coils collected committee commonly computer considerations consistent content contrast coronal corrected correction custom dark development dictated diffusion distortion done double duration encoding evaluated exceed excellent eyes features final frequency function generally gradient head hill hour human imperfect implemented increasing institutional interpolation isotropic leading limits long longer looking macaques maps martin match minimize minimized motion north occurred opportunities optimal orientation package pixel placed position positioning practical prevented previous primate prone protocol psychiatry pulse radiology rapid readout reduce reduction refer reflects required resolution resting reveal review rhesus running sampling scanning science sciences sections selected selection selections sensitivity significantly slice slices smaller software spaces spacing spatial sphinx striking structural summary susceptibility susceptible system taken theory thin tissue turbo turned typical uniform uniformity unique univ vertical vessels white yield