Regionally Specific Association Between Reduced CVR and Cortical Thinning in the Pediatric Population with Sickle Cell Disease

Keywords

ability administration affect anatomical appearing arch assessment association atlas bilateral blood bold brain cell central cerebral certain channel child children civet clasp clinical cognitive coil compromised computationally computed computer constrained control controlled controls converted correction corrections correlated correlating correlation cortex cortical cycles decline deficits defined degree delivered dependent development direct disease disorder disruptions even example executive finding flow function future genetic globally head health healthy history hospital human hypothesized identify impairment include increasingly indicate inferior integrity intensive jeopardize kirk linear maintenance mapping maps mask matrix measure measures moderate neurological normalized objectives overt oxygen patients pediatric percent physiological pipeline poor population post potential potentially previously processed program programmed proximities reactivity recently reduced regional regionally registration regulation relation resolution response scanner segmentation serve severity sick sickle significantly slice slices space spatially standardized still stimulus strong strongly structural suffering suggesting surface susceptible symptoms temporal thinner thinning tidal unknown vascular volumes waveform whether whole wise