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Abstract #3566

Language Reorganization Following Anterior Temporal Lobectomy in Patients with Chronic Intractable Epilepsy

S. Senthil Kumaran1, Kapil Chaudhary2, Manjari Tripathi2, Sarat P. Chandra3

1Department of NMR, All India Institute of Medical Sciences, New Delhi, Delhi, India; 2Department of Neurology, All India Institute of Medical Sciences, New Delhi, Delhi, India; 3Department of Neuro-Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India

Functional MRI was used to study the impact of anterior temporal lobectomy (ATL) on language functions in patients with left temporal lobe epilepsy (LTLE). FMRI Paradigm included multiple components of language for observing bold activation in cortical language networks. The results suggest that language areas specially involved in complex syntactic-semantic tasks to be preserved during ATLR for maximum conservation of functionality, and post-durgincal plasticity in language functions were observed.

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Keywords

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