Jie Yang1,
Zhifeng Kou1,2, Robert Dean Welch3, Randall Benson4,
Ramtilak Gattu2, Valerie Mika3, Ewart Mark Haacke1
1Radiology,
Wayne State University School of Medicine, Detroit, MI, United States; 2Biomedical
Engineering, Wayne State University, Detroit, MI, United States; 3Emergency
Medicine, Wayne State University School of Medicine, Detroit, MI, United
States; 4Center for Nerologic Studies, Novi, MI, United States
Using SWI and resting-state fcMRI methods, this study aims to provide neuroimaging biomarkers that may reveal neurovascular deficits and changes in function connectivity of patients post traumatic brain injury at the acute stage. Subtle medullary vein damage seen by SWI and disrupted resting-state networks indicated by fcMRI, together with the changes in these MRI indices over time will be imaging biomarkers complimentary to routine clinical evaluation of mTBI patients.