Meeting Banner
Abstract #3548

Standard Deviation of T1ρ and T2 Relaxation Times Show Regional Changes in Hip Articular Cartilage of Patients with FAI

Stephen J. Matzat1, Emily J. McWalter2, Weitian Chen3, Marc R. Safran4, Garry E. Gold2, 5

1Stanford University, Stanford, CA, United States; 2Department of Radiology, Stanford University, Stanford, CA, United States; 3MR Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; 4Department of Orthopaedic Surgery, Stanford University, Stanford, CA, United States; 5Department of Bioengineering, Stanford University, Stanford, CA, United States

Patients with femoroacetabular impingement (FAI) commonly experience chondral damage in the anterior acetabulum and may be at risk for early development of osteoarthritis. Conventional MR techniques are not sensitive to detecting these early changes in the hip. This study tests if quantitative MR methods using T1ρ and T2 relaxation times can detect regional changes in patients with FAI. Results show that standard deviation of T1ρ and T2 relaxation times (as measures of cartilage heterogeneity) are elevated in cartilage of the anterior acetabulum, indicating that patients with FAI exhibit sings of early osteoarthritis.

Keywords

abstract acquisition additionally aims alternate although amount analyzing anterior applied arthritis articular benefits bioengineering breakdown capture cartilage cause channel clinical coil commonly confirm consistent contribute created damage damaged defects degradation delayed detect detected detecting determine development deviation deviations diluting disease distribute done early either elevated enhanced exercise exhibit explain exponential femoral finding findings fluid foundation frequency gadolinium gold happen heterogeneity identify immediately impingement indications injected injection intervals invest isolated joint knee laboratory layers limitation lock management mapped maps matrix measured minimize mono morphologic osteoarthritis paired park part patient patients physiological pockets posterior presence preventing progression progressive promise prone quantitative radiology rather reasons recruited referral regional risk saline scanner science segmented sensitive several signs skeletal slice slices spin suggests surgery surrogate table thought throughout tool tracking unaffected uniform useful